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January 1, 2001Chemical Communications

Vitamin C induced decomposition of lipid hydroperoxides: direct evidence of genotoxin–DNA binding detected by QCRS

Karl D. Pavey Mijan Miah Flavia Fucassi Peter J. Cragg Frank Paul

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Abstract

We report direct evidence for human DNA-binding to precursors of mutagenic lesion-inducing compounds, produced form the vitamin C induced decomposition of lipid hydroperoxides, using a quartz crystal resonant sensor assay.

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Pavey et al. (2001) studied this question.

synapsesocial.com/papers/6ac4ac2dd02c3c2b870596a4 https://doi.org/10.1039/b105766a

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