Comparison of Diagnostic Value of Myocardial Perfusion Scan and Coronary Angiography in the Detection of Coronary Artery Disease in Ardabil

Background: Cardiovascular diseases are among the leading causes of mortality worldwide, accounting for over 30% of deaths in developed countries.Various imaging techniques have been developed to identify the pathology of these diseases.This study aimed to evaluate the diagnostic value of myocardial perfusion scanning in detecting coronary artery disease (CAD) compared with coronary angiography in Ardabil during 2021-2022.methods: In this descriptive study, data from 101 patients were extracted using a standardized checklist through medical record review.The checklist included demographic information such as age and sex.Coronary angiography data included the severity of coronary artery involvement (single-vessel, two-vessel, or three-vessel) for each patient.Myocardial perfusion scan findings were also collected from patient records. Results:The mean age of the patients was 57.8 ± 11.5 years, and 51.5% were female.Based on coronary angiography as the gold standard, 79.2% of patients had abnormal findings, while this rate was 86.1% for myocardial perfusion scans.Compared with angiography, the sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of myocardial perfusion scans were 88.7%, 23.8%, 81.6%, 35.7%, and 75%, respectively.Sensitivity for the LAD, LCX, and RCA arteries was 86%, 84%, and 77%, respectively.No significant differences were observed between the two methods regarding the degree of coronary artery stenosis or based on age and sex (P>0.05).Overall agreement between myocardial perfusion scans and angiography was low (κ=0.14). Conclusion:Myocardial perfusion scanning has reasonable sensitivity for detecting coronary artery disease; however, due to low agreement with angiography, it is not sufficient for definitive diagnosis on its own.