Evaluation of the Correlation Between Myocardial Perfusion Scan Findings and Invasive Coronary Angiography Results

Background: Non-invasive and cost effective treatments of coronary artery disease (CAD) are a health priority and a current necessity. Objectives: This study aimed at comparing the results of myocardial perfusion imaging (MPI) with coronary angiography findings in the diagnosis of CAD. Methods: This cross sectional study included 155 patients with stable angina, who were referred to Kowsar hospital, Semnan, Iran, from May 2013 to April 2014. After confirmation of positive perfusion imaging, angiography was performed within 3 months. Myocardial perfusion imaging results were categorized as mild, moderate and severe, and also in coronary angiography, narrowing of more than 50% of the vessels was considered as significant stenosis. Results: Mean age was 58.3 ± 11.5 and 82 (52.9%) of the participants were male. According to MPI, the lateral wall of the myocardia (44.5%) was the most common affected area. Abnormal angiographic findings were reported in 47.7% (n = 74) of the patients. The number of affected vessels in the angiography had a positive correlation with the scan score (r = 0.501 and P = 0.001). The MPI had less than 50% sensitivity and more than 72% specificity. Conclusions: This study indicated that MPI and coronary angiography findings had a positive correlation. The sensitivity of MPI was less than optimal, and it may be better if supplemented by other diagnostic techniques for diagnosis CAD.