Key result
Reduced LVEF, smoking, and surgical factors are linked to higher pulmonary embolism risk after OPCAB.
Why the study?
Acute pulmonary embolism is a serious complication after off-pump coronary artery bypass grafting, but its risk factors have not been fully analyzed.
Observational (n=707)
No
Answers are grounded in this paper and cite their sources.
These risk factors may inform perioperative vigilance after off-pump CABG; hypothesis-generating and requires prospective validation.
OBJECTIVE: Acute pulmonary embolism (APE) is a serious complication after off-pump coronary artery bypass grafting (OPCABG). We aimed to analyze the risk factors for APE in patients with OPCABG. METHODS: In this retrospective, observational study, patients with OPCABG who were treated in our hospital from 1 January 2018 to 31 March 2020 were included. The basic characteristics of patients and results of preoperative laboratory examinations were collected and analyzed. RESULTS: A total of 707 patients with OPCABG were included and the incidence of APE was 3.21%. Left ventricular ejection fraction (LVEF), a history of smoking, number of bypass grafting, duration of surgery, and age were significant risk factors for APE in patients with OPCABG. The areas under the curves of LVEF, number of bypass grafting, duration of surgery, and age were 0.773, 0.759, 0.738, and 0.723, respectively. The cutoff values of LVEF, number of bypass grafting, duration of surgery, and age were 59.84, 3.18, 237.42, and 73.28, respectively. CONCLUSIONS: LVEF, a history of smoking, number of bypass grafting, duration of surgery, and age may be risk factors for APE in patients with OPCABG. Early measures should be taken to target these risks to prevent APE.
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Cao et al. (2020) conducted an observational in Coronary heart disease (n=707). Reduced left ventricular ejection fraction (LVEF ≤59.84%) vs. Patients with LVEF >59.84% was evaluated on Acute pulmonary embolism (OR 4.382, 95% CI 2.534-5.507, p=0.018). Decreased left ventricular ejection fraction, a history of smoking, a higher number of bypass grafts, a longer surgery duration, and older age significantly increased the risk of acute pulmonary embolism following off-pump coronary artery bypass grafting.
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