Key result
SCLC cardiac metastasis mimics STEMI despite the absence of obstructive CAD.
Why the study?
Cardiac metastasis can present with ST-segment elevation mimicking STEMI, but its recognition and differentiation from obstructive CAD remain challenging.
Case Report (n=1)
No
Cardiac metastasis should be considered in the differential diagnosis of ST-elevation myocardial infarction with non-obstructive coronary arteries, especially in patients with a known malignancy.
Answers are grounded in this paper and cite their sources.
Cardiac metastasis warrants consideration in STEMI without obstructive CAD; single case leaves open need for systematic validation.
A 52-year-old woman with a history of lung cancer presented with progressive shortness of breath. Her ECG showed evidence of ST-elevation myocardial infarction (STEMI) though no evidence of obstructive coronary artery disease (CAD) was seen on coronary angiography. Further imaging with CT and cardiac MRI (CMRI) demonstrated tumor, likely metastatic cancer, within myocardial tissue. This case is demonstrative of the possible relationship between ST-segment elevation on ECG and corresponding tumor invasion and highlights the differential diagnoses of STEMI, including cardiac metastasis.
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A 2023 study conducted a case report in Cardiac Metastasis mimicking ST-Elevation Myocardial Infarction (n=1). Cardiac metastasis was evaluated. Cardiac metastasis from primary small cell lung cancer can present with ST-segment elevation on ECG mimicking an acute myocardial infarction despite the absence of obstructive coronary artery disease.
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