Key result
Surgical resection of solitary RV metastasis yields complete local response and ~9-month progression-free survival.
Why the study?
Cardiac metastasis from lung cancer is rare and often clinically silent, with limited data on optimal management and the role of surgery in improving survival.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
Surgical resection of an isolated cardiac metastasis can be a safe and successful therapeutic option providing local control in patients with oligo-progressive lung cancer.
Introduction: Cardiac metastasis (CM) is a rare lung cancer location. It often remains clinically silent but may cause life-threatening complications. Better survival rates thanks to the immunotherapy revolution and the improving performance of imaging lead to an increasing number of CM diagnosis. Case Presentation: We report a case of a 54-year-old woman who was diagnosed with a stage IIIa non-small cell lung cancer. She developed a right ventricular CM without symptoms during treatment by immunotherapy after concurrent chemoradiotherapy. Cardiac magnetic resonance imaging confirmed the presence of an endocavitary lesion in the right ventricle apex. Complete surgical resection through a right ventriculotomy was performed. Conclusion: The diagnosis of similar cases has become more frequent due to immunotherapy and more advanced imaging technology. Our case report also highlights the fact that CM surgery has to be considered as a successful therapeutic option in those oligo-progression situations. Guidelines on the management and treatment of lung cancer CM are needed as well as larger studies to evaluate the survival benefit from surgical treatment.
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Borne et al. (2023) conducted a case report in Solitary right ventricular cardiac metastasis from lung adenocarcinoma (n=1). Complete surgical resection (right ventriculotomy) was evaluated on Progression-free time and local response. Complete surgical resection of a solitary right ventricular metastasis resulted in a sustained complete local response and 9 months of progression-free survival.
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