Key result
Bare-metal stent implantation shows ~59% cardiovascular event-free survival over 12-year follow-up.
Why the study?
The long-term effects of intracoronary balloon-expandable Palmaz-Schatz stents in patients with single-vessel coronary artery disease were unknown.
Cohort (n=2,391)
No
Modest long-term event-free survival after bare-metal stenting; leaves open durability of contemporary stents in extended real-world follow-up.
The long-term effects of intracoronary stents in human are unknown. This is the first 9-year follow-up report of single-vessel-disease patients treated with the Palmaz-Schatz stent. Between March and December 1989, out of the 107 patients undergoing Palmaz-Schatz stent implantation, 71 (66%) had single-vessel disease. The average age of these patients was 58+/-9 years and 79% were men. At 9 years, follow-up was obtained for 90.1% and major adverse clinical events consisted of 4 deaths giving a global survival rate of 95.8%, 7 myocardial infarction, 3 bypass surgeries, and 16 repeat percutaneous revascularization procedures. The 9-year event-free survival rate was 60%, and 81.7% of the patients were free from death, myocardial infarction, and bypass surgery. Multivariate analysis showed that the only predictive factor of major adverse clinical events was the presence of diabetes mellitus (P<0.004). Cathet. Cardiovasc. Intervent. 50:170-174, 2000.
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Karam et al. (2000) conducted a cohort in Coronary artery disease (n=2,391). Bare-metal stent implantation was evaluated on Cardiovascular event-free survival. In a registry of 2,391 patients who underwent bare-metal stent implantation, the cardiovascular event-free survival rate was 58.5% over a mean follow-up of 149 months.
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