Assessing the Maternal and Fetal Outcomes of Antenatal Women with Severe Mitral Stenosis Undergoing Balloon Mitral Valvotomy at a Tertiary Care Centre

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Severe Mitral Stenosis in Pregnancy. Intervention: Balloon Mitral Valvotomy (BMV) / Percutaneous Transmitral Commissurotomy (PTMC). Primary outcome: Clinical, maternal, and fetal outcomes.

Q: What does this research mean for the field?

Balloon mitral valvotomy is safe and effective in pregnant women with severe mitral stenosis, significantly improving maternal clinical and echocardiographic profiles and resulting in favorable fetal outcomes. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Sathish Kumar Subburaj; Saravanan Ramasamy Rathinam; Ramesh Ramachandran; Balasubramanian Sundaram; Selvarani Gnanamuthu; G.S. Sivakumar; Nandhini Sakthivadivel

doi:10.1016/j.ihjcvr.2026.10.002

October 1, 2026IHJ Cardiovascular ReportsOpen Access

Assessing the Maternal and Fetal Outcomes of Antenatal Women with Severe Mitral Stenosis Undergoing Balloon Mitral Valvotomy at a Tertiary Care Centre

View Full Paper

Ask AI

Bookmark

Share

Key result

Balloon mitral valvotomy improves clinical profiles and fetal outcomes in pregnant women with severe mitral stenosis.

Why the study?

The clinical, maternal, and fetal outcomes of pregnant women with severe mitral stenosis undergoing percutaneous transmitral commissurotomy during pregnancy were not well characterized.

Does percutaneous transmitral commissurotomy (BMV) improve clinical, maternal, and fetal outcomes in pregnant women with severe mitral stenosis?

Key Points

To evaluate the clinical, maternal, and fetal outcomes of antenatal women with severe mitral stenosis undergoing percutaneous transmitral commissurotomy.
Single-center prospective cohort observational study.
Enrolled pregnant women with severe mitral stenosis undergoing percutaneous transmitral commissurotomy.
Assessed maternal clinical and echocardiographic profiles as well as fetal outcomes before and after the procedure.
Balloon mitral valvotomy significantly improved maternal clinical and echocardiographic profiles.
Moderate commissural mitral regurgitation occurred as a complication but was managed conservatively.
Low-birth-weight neonates were observed but were not attributed to the balloon mitral valvotomy procedure.

Study Design

Type

Cohort

Multicenter

No

Structured PICO

Does percutaneous transmitral commissurotomy (BMV) improve clinical, maternal, and fetal outcomes in pregnant women with severe mitral stenosis?

P

Population

Pregnant women with severe mitral stenosis undergoing balloon mitral valvotomy at a single tertiary care center.

E

Exposure

Percutaneous transmitral commissurotomy (PTMC) / Balloon mitral valvotomy (BMV)

O

Outcome

Clinical, maternal, and fetal outcomes, including echocardiographic profiles

Balloon mitral valvotomy is a safe and clinically effective intervention for pregnant women with severe mitral stenosis, resulting in improved maternal profiles and favorable fetal outcomes.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Supports BMV consideration in pregnant severe MS; leaves open randomized confirmation of maternal-fetal benefits.

Abstract

Objective To evaluate the clinical, maternal, and fetal outcomes of pregnant women undergoing percutaneous transmitral commissurotomy (PTMC) during pregnancy. Methods A single-center prospective cohort observational study. Pregnant women with severe MS who underwent PTMC were included. The patients were monitored before and after the procedure, and fetal and maternal outcomes were assessed. Results BMV significantly enhanced the clinical and echocardiographic profiles of pregnant women with severe MS. Low-birth-weight babies were noted, unrelated to BMV. Moderate commissural MR occurred but was managed conservatively. Conclusion BMV is safe and effective in pregnant women with severe MS resulting in favorable fetal outcomes.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Subburaj et al. (2026) conducted a cohort in Severe Mitral Stenosis in Pregnancy. Balloon Mitral Valvotomy (BMV) / Percutaneous Transmitral Commissurotomy (PTMC) was evaluated on Clinical, maternal, and fetal outcomes. Balloon mitral valvotomy significantly enhanced the clinical and echocardiographic profiles of pregnant women with severe mitral stenosis and resulted in favorable fetal outcomes.

synapsesocial.com/papers/6ac5af849e451472f9bc9569 https://doi.org/10.1016/j.ihjcvr.2026.10.002

View Full Paper

Ask AI

Bookmark

Share

Assessing the Maternal and Fetal Outcomes of Antenatal Women with Severe Mitral Stenosis Undergoing Balloon Mitral Valvotomy at a Tertiary Care Centre

Key Points

Study Design

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Assessing the Maternal and Fetal Outcomes of Antenatal Women with Severe Mitral Stenosis Undergoing Balloon Mitral Valvotomy at a Tertiary Care Centre

Key Points

Study Design

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading