⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

September 15, 2026Antiviral ResearchOpen Access

Identification of 1,2-dihydroquinazolin-2-ones kinase inhibitors as anti-coronavirus agents

Blanca Martínez-Arribas Rosario Díaz-González Jenelle Weaver Madeline Walden Caden Mackenzie Amy B. Dounay María C. Ramos Olga Genilloud Luis M. Ruiz‐Pérez Marco Mottinelli Lori Ferrins Dolores González‐Pacanowska

View Full Paper

Ask AI

Bookmark

Share

Abstract

< 3 μM and favourable selectivity belong to a series of 1,2-dihydroquinazolin-2-ones, representing a novel class of antivirals.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Martínez-Arribas et al. (2026) studied this question.

synapsesocial.com/papers/6ac5b1fbb77bd4c7c183cd2e https://doi.org/10.1016/j.antiviral.2026.106534

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcriptionOriginal Research · 2006 · 96 citations
2Optimization of Physicochemical Properties and ADME for 2,4-Substituted 1<i>H</i>-Pyrrolo[2,3<i>b</i>]pyridines Inhibitors of Trypanosome Proliferation2025 · 3 citations
3Anti‐SARS‐CoV‐2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID‐19 therapyOriginal Research · 2022 · 22 citations
4A Shift in Thinking: Cellular Thermal Shift Assay-Enabled Drug DiscoveryOriginal Research · 2023 · 15 citations
5Suppression of Coronavirus Replication by Inhibition of the MEK Signaling PathwayOriginal Research · 2006 · 99 citations

More related papers

Tat is a multifunctional viral protein that modulates cellular gene expression and functions2017
Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign2014
Pharmacophore Identification and Structure–Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of <i>Trypanosoma brucei</i>2024

More from Antiviral Research

Construction of a suckling mouse model based on an EV-C96 clinical isolate and its application in drug screening and vaccine developmentThu,
The Golgi-resident protein ACBD3 facilitates the interaction between enteroviral 3A proteins and Exportin-1Mon,