Key result
Warfarin use in epistaxis is linked to higher readmission rates without altering in-patient stay duration.
Why the study?
The impact of continuing warfarin on management, readmission rates, and length of stay in epistaxis patients was unclear to guide treatment protocols.
Cohort (n=176)
Supports continuing warfarin if INR therapeutic in epistaxis; higher readmissions leave optimal protocols open for prospective study.
OBJECTIVE: This study aimed to compare management, readmission rates and length of in-patient stay amongst warfarinised and non-warfarinised patients to ascertain future treatment protocols. METHODS: A 12-month retrospective review was conducted of ENT epistaxis admissions. Admission details such as length of in-patient stay, clotting profile and management plan were recorded. Comparisons of management and outcome for warfarinised and non-warfarinised patients were made using the Fisher's exact paired t-test. RESULTS: Of 176 epistaxis patients admitted, 31 per cent were warfarinised, 18 per cent were on another form of anticoagulation or antiplatelet therapy, and 51 per cent were not on any medication that might impose a bleeding risk. The international normalised ratio at admission was high in 13 per cent of warfarinised patients; the remaining patients had therapeutic or sub-therapeutic international normalised ratios and so warfarin was continued. The mean in-patient stay was similar for all cohorts; however, warfarinised patients had a higher readmission rate. CONCLUSION: Warfarinised epistaxis patients may be safely managed without stopping their anticoagulation therapy, provided their international normalised ratio is at therapeutic or sub-therapeutic levels. By continuing regular anticoagulation therapy, warfarinised patients may be discharged without delay.
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Bola et al. (2015) conducted a cohort in Epistaxis (n=176). Warfarin therapy vs. Non-warfarinised (no medication imposing a bleeding risk) was evaluated on Management, readmission rates and length of in-patient stay. Warfarinized epistaxis patients experienced similar mean in-patient stay durations but higher readmission rates compared to non-warfarinized cohorts.
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