A Rare Cause of Childhood Encephalitis: Human Coronavirus HKU1

This is the authors' abstract. We don't add key points for this paper.

Coronaviruses are primarily known for causing respiratory infections; however, emerging evidence suggests they may also cause neurological complications. We present a lethal case of encephalitis in a previously healthy five-year-old boy, in whom Human Coronavirus HKU1 (HCoV-HKU1) was identified through respiratory microarray and postmortem cerebrospinal fluid (CSF) PCR analysis. This report underscores the necessity of including coronaviruses in the differential diagnosis of pediatric encephalitis of unknown etiology.