Key result
Coronavirus HKU-1 infection can mimic ACS with significant chest discomfort and high serial troponin.
Why the study?
The heart is rarely affected by HKU-1 coronavirus infection, and cases presenting as acute coronary syndrome are uncommon and not well characterized.
Case Report (n=1)
Coronavirus HKU-1 infection can rarely present with troponin leakage and chest pain mimicking acute coronary syndrome.
Answers are grounded in this paper and cite their sources.
Consider HKU-1 in ACS-like troponin elevation; leaves open whether viral testing changes management.
In the last five decades, human corona virus (CoVs) have been linked to upper respiratory tract infections such as the common cold. HKU-1 infection was first discovered in Hong Kong in 2014. Unlike other CoV strains, HKU-1 infection usually results in a moderate respiratory infection. The heart is rarely affected by HKU-1 infection. There have been a few cases of HKU-1 infection presenting as pericarditis and pericardial effusion. We present a case of CoV HKU-1 infection presenting with significant chest discomfort and high serial troponin-I levels, which was suspected to be acute coronary syndrome.
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Jadhav et al. (2025) conducted a case report in Coronavirus HKU-1 infection presenting as acute coronary syndrome (n=1). Coronavirus HKU-1 infection was evaluated on Troponin leakage syndrome / acute coronary syndrome presentation. Coronavirus HKU-1 infection can present with significant chest discomfort and high serial troponin-I levels mimicking acute coronary syndrome.
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