Key result
COVID-19 infection is linked to fatal constrictive pericarditis in a novel case report.
Why the study?
There was no prior report of constrictive pericarditis associated with SARS-CoV-2 infection (COVID-19).
Case Report (n=1)
No
Possible constrictive pericarditis in COVID-19 merits awareness; single case leaves association hypothesis-generating.
BACKGROUND: Since December 2019, there has been an increasing number of patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) around the world. As of March 2020, the World Health Organization declared a global pandemic. CASE PRESENTATION: To our best knowledge, this is the first report of a patient with SARS-CoV-2 infection presenting with constrictive pericarditis, possibly from the COVID infection. She was presented after a week of fever, persistent dry cough, and diarrhea. She received a single dose of hydroxychloroquine 400 mg, Oseltamivir 75 mg every 12 hours, lopinavir/ritonavir (Kaletra) 400/100 mg every 12 hours, and levofloxacin 750 mg daily. After 24 hours, she was immediately transferred to the Intensive Care Unit (ICU) because of dyspnea and progressive respiratory failure with a drop of the O2 saturation to 70%. CONCLUSION: After a week of progress, her respiratory condition deteriorated again. She was re-admitted to the ICU and she expired. She died due to constrictive pericarditis, most probably caused by SARS-CoV-2.
No takes yet. Share an insight, caveat, or question.
SeyedAlinaghi et al. (2020) conducted a case report in Constrictive pericarditis associated with COVID-19 (n=1). SARS-CoV-2 infection was evaluated. A female patient with SARS-CoV-2 infection presented with constrictive pericarditis and subsequently died due to progressive respiratory failure, suggesting a potential association between COVID-19 and constrictive pericarditis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: