Key result
Six-Minute Walk Test assesses exertion tolerance in adolescents with systemic lupus erythematosus.
Why the study?
Cardiovascular pathology leading to heart failure is the main cause of decreased quality of life and mortality in adolescents with systemic lupus erythematosus, with early myocardial dysfunction manifesting as reduced tolerance to routine physical activities.
Cross-Sectional (n=46)
6MWT assessment in adolescent SLE remains preliminary; leaves open its value for detecting early cardiac involvement.
In modern medicine, the issue of rheumatic diseases remains one of the most significant and socio-economically impactful problems due to the high rates of disability and loss of working capacity among these patients. The main cause of decreased quality of life and mortality in patients with systemic lupus erythematosus (SLE) is cardiovascular pathology, leading to the development of heart failure. An early symptom of myocardial dysfunction is the patient's loss of ability to perform routine physical activities in daily life. The aim of the study was to assess tolerance to minimal physical exertion in adolescents with systemic lupus erythematosus. A total of 46 adolescents with SLE were examined. They underwent the Six-Minute Walk Test (6MWT) with measurement of several parameters at rest and during the first minute of recovery following exertion.
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Tetiana Holovko (2026) conducted a cross-sectional in Systemic lupus erythematosus (n=46). Systemic lupus erythematosus was evaluated on Tolerance to minimal physical exertion assessed via Six-Minute Walk Test parameters.
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