Key result
Full-S3 functional mapping evaluated for feasibility and acute hemodynamics during scar-related VT ablation.
Why the study?
Functional substrate mapping with ventricular extrastimuli may unmask abnormal signals during scar-related VT ablation but its feasibility and acute hemodynamic impact are uncertain.
What is the feasibility and acute hemodynamic safety of a full-S3 functional mapping protocol during scar-related ventricular tachycardia ablation?
What is the feasibility and acute hemodynamic safety of a full-S3 functional mapping protocol during scar-related ventricular tachycardia ablation?
The study evaluates whether an S3 functional mapping protocol with two extrastimuli is feasible and safe from an acute hemodynamic perspective during scar-related VT ablation.
Functional substrate mapping with ventricular extrastimuli can unmask hidden abnormal signals and deceleration zones (DZs) not identified during baseline pacing. The S3 protocol extends high-density whole-chamber mapping to two extrastimuli and may reduce reliance on prolonged activation mapping of sustained ventricular tachycardia (VT).1 Because S3 extrastimulation may precipitate acute hemodynamic decompensation (AHD), particularly in advanced structural heart disease under general anesthesia, we assessed the feasibility and acute hemodynamic outcomes of a full-S3 protocol.
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Pierucci et al. (2026) studied Scar-Related Ventricular Tachycardia. full-S3 functional mapping protocol was evaluated on Feasibility and acute hemodynamic outcomes. A full-S3 functional mapping protocol was assessed for feasibility and acute hemodynamic outcomes during scar-related ventricular tachycardia ablation, though specific results were not reported.
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