Key result
CKD shows no significant difference in 12-month AF-free survival after pulsed field ablation.
Why the study?
AF and CKD are prevalent conditions with shared risk factors, but safety and efficacy of pulsed field ablation for AF in CKD patients were not well characterized.
Cohort (n=2,269)
Hazard Ratio: 1.2 (95% CI 0.93–1.59)
p-value: p=0.1
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Cohort study finds similar rhythm control but higher acute kidney injury after pulsed field ablation in kidney disease, indicating a need for careful periprocedural renal management.
Rodriguez et al. (2026) conducted a cohort in Atrial fibrillation (n=2,269). Chronic kidney disease vs. No chronic kidney disease was evaluated on 12-month AF-free survival (HR 1.20, 95% CI 0.93-1.59, p=0.1). In patients undergoing pulsed field ablation for atrial fibrillation, chronic kidney disease was associated with comparable 12-month AF-free survival versus no CKD (HR 1.20; 95% CI 0.93-1.59; P=0.1).
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