Key result
Calcium and vitamin D replacement yields full recovery of LV function in infant dilated cardiomyopathy.
Why the study?
Dilated cardiomyopathy is mostly idiopathic or genetic, but hypocalcemia is a rare reversible cause that requires further clinical awareness.
Case Report (n=1)
No
Supports screening for hypocalcemia in infant DCM; leaves open need for prospective validation.
Dilated cardiomyopathy, which mostly has an idiopathic etiology or is caused by genetic inheritance or infection, can cause irreversible congestive heart failure. Hypocalcemia is a rare etiology of reversible dilated cardiomyopathy. Here we report the case of a two-month-old girl with congestive heart failure who was diagnosed as having dilated cardiomyopathy secondary to hypocalcemia. After calcium and vitamin D replacement therapy, the patient showed a rapid reduction in hypocalcemic tetany and a rapid recovery of left ventricular function. The cause of the hypocalcemia was vitamin D deficient rickets. She was exclusively breast-fed as an infant, and her mother had a vitamin D deficiency and was diagnosed with osteomalacia.
No takes yet. Share an insight, caveat, or question.
Chang et al. (2010) conducted a case report in Dilated cardiomyopathy secondary to hypocalcemia with vitamin D deficient rickets (n=1). Calcium and vitamin D replacement therapy was evaluated on Clinical recovery of left ventricular function and resolution of hypocalcemic tetany. Calcium and vitamin D replacement therapy resulted in rapid resolution of hypocalcemic tetany and full recovery of left ventricular function in an infant with dilated cardiomyopathy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: