A systemic streptococcal infection in cultured bullfrogs in Brazil was characterized by necrotizing splenitis and hepatitis with hepatic and renal hemorrhage. A non-hemolytic Group B Streptococcus appeared to be the cause of the lesions, and the stimulus for the splenic reticuloendothelial hyperplasia observed in the animals. Stress may have been a factor in the development of the pathological condition.
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Amborski et al. (1983) studied this question.
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