Key result
Transcatheter PFO closure prevents recurrent ischemic stroke in a middle-aged woman at 8 months.
Why the study?
Recurrent ischemic strokes of embolic origin present diagnostic challenges, particularly in identifying patent foramen ovale as the probable cause and guiding secondary prevention.
Case Report (n=1)
No
Hypothesis-generating for PFO closure in recurrent embolic stroke; prospective trials needed before clinical adoption.
А clinical case of a young patient with recurrent ischemic strokes is presented. The problems of diagnostic embolic strokes are discussed. We set out the algorithm for identifying patients, in whom patent foramen ovale is the most probable cause of embolic stroke. Detailed consideration of imaging diagnostic methods possibility is included. Hypothesis of probable source of cardioembolism from patent foramen ovale is presented. Recommendations for the secondary prevention of recurrent ischemic stroke, associated with patent foramen ovale, are provided. We also considered the issues of antithrombotic treatment.
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Komarov et al. (2022) conducted a case report in Recurrent embolic strokes and patent foramen ovale (n=1). Transcatheter patent foramen ovale closure was evaluated on Recurrent ischemic stroke. Transcatheter closure of a patent foramen ovale in a 56-year-old woman with recurrent embolic strokes prevented further ischemic episodes over an 8-month follow-up.
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