Palmar-Plantar Skin Changes and Cytarabine

Letters and Corrections1 November 1985Palmar-Plantar Skin Changes and CytarabineWIM G. PETERS, M.D., ROEL WILLEMZE, M.D.WIM G. PETERS, M.D.Search for more papers by this author, ROEL WILLEMZE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-5-805_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In recent months several authors in your journal have discussed the palmar-plantar erythrodysesthesia syndrome associated with chemotherapy. Lokich and Moore (1) stated that the syndrome is causally related to chemotherapy in that it recedes with interruption of drug infusion and reappears when drug therapy is reinstituted. Baer and colleagues (2) described two patients with almost identical toxicity when cytarabine was given as a bolus over 5 to 10 minutes. In their opinion high peak drug levels might be implicated in the pathogenesis of this syndrome. Vogelzang and Ratain (3) described the cases of 36 patients treated with...References1. LOKICHMOORE JC. Chemotherapy-associated palmar-plantar erythrodysesthesia syndrome. Ann Intern Med. 1984;101:798-800. LinkGoogle Scholar2. BAERKINGWOLFF MLS. Palmar-plantar erythrodysesthesia and cytarabine [Letter]. Ann Intern Med. 1985;102:556. LinkGoogle Scholar3. VOGELZANGRATAIN NM. Cancer chemotherapy and skin changes [Letter]. Ann Intern Med. 1985;103:303-4. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Leiden University Medical Center 2333 AA, Leiden the Netherlands PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAntimetabolite ReactionsBullous acral erythema: an additional consideration in the differential diagnosis of pauci-inflammatory subepidermal bullae*Eritema acral inducido por quimioterapiaChemotherapy-Induced Acral Erythema: A Clinical and Histopathologic Study of 44 CasesPalmar-plantar erythrodysesthesiaRecurrent palmar-plantar erythrodysaesthesia following high-dose cytarabine treatment for acute lymphoblastic leukemiaIncidence and Severity of Hand–Foot Syndrome in Colorectal Cancer Patients Treated with Capecitabine: A Single-Institution ExperienceAntineoplastic Therapy???Induced Palmar Plantar Erythrodysesthesia (???Hand-Foot???) SyndromeHigh Incidence of Chemotherapy-Induced Acral Erythema in Female Patients with non-Hodgkin's Lymphoma Treated with the Vacop-B RegimenA Case of Acral Erythema Induced by Methotrexate.Three Cases of Chemotherapy-induced Acral ErythemaTreatment of cytarabine acral erythema with corticosteroidsChemotherapy-induced acral erythemaErythema and swelling of ears after treatment with cytarabine for leukemiaHigh-dose cytosine arabinoside: pharmacological and clinical aspectsHypersensitivity reactions from antineoplastic agents 1 November 1985Volume 103, Issue 5Page: 805-805KeywordsChemotherapyDrug therapyDrugsPathogenesisToxicity Issue Published: 1 November 1985 PDF DownloadLoading ...