EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease: guidelines, clinical reality and health economic aspects

An increase in the prevalence of obesity and the metabolic syndrome as a result of changes in eating habits, both quantitative (over-eating) and qualitative (e.g. high fructose consumption), and a lack of exercise contribute to fatty liver disease. Non-alcoholic fatty liver disease (NAFLD) is a clinical histological spectrum ranging from steatosis to non-alcoholic steatohepatitis (NASH) and affects more than 30% of the general population [1].