Key result
Mobile LV thrombus forms within three weeks and resolves in two days despite subtherapeutic anticoagulation.
Why the study?
The transient nature of left ventricular thrombosis and its implications for treatment decisions and echocardiographic screening in embolism patients were not well understood.
Case Report (n=1)
Rapid LV mural thrombus formation and resolution possible in cardiomyopathy; leaves open optimal anticoagulation dosing and serial echo monitoring frequency.
A left ventricular mural thrombus with a mobile appendix of 0.5 x 0.5 x 3 cm was shown by two dimensional echocardiography in a 31 year old man who had dilated congestive myocardial disease. Serial echocardiograms showed formation of the thrombus within three weeks and uncomplicated disappearance of the mobile clot within less than two days. Heparin and phenprocoumon were given in doses generally not accepted to affect left ventricular thrombosis adequately. Such transience of left ventricular thrombosis may be worth considering when deciding whether to treat patients with thrombi accidentally demonstrated by echocardiography; it also might explain some of the many negative examinations in the echocardiographic screening of patients with embolism.
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Egeblad et al. (1983) conducted a case report in Left ventricular mural thrombus and dilated congestive myocardial disease (n=1). Heparin and phenprocoumon was evaluated on Formation and disappearance of left ventricular thrombus. A left ventricular mobile clot formed within three weeks and rapidly disappeared within two days despite subtherapeutic anticoagulation.
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