Key result
Hypertension was associated with a significantly prolonged visual evoked potential P100 latency (106 msec) compared to normotensive controls (99.76 msec, p < 0.001).
Why the study?
Hypertension may affect the visual pathway, but its impact as assessed by visual evoked potential has not been clearly established.
Does newly diagnosed hypertension affect the visual pathway as measured by visual evoked potential latency and amplitude?
Case-Control (n=50)
No
Does newly diagnosed hypertension affect the visual pathway as measured by visual evoked potential latency and amplitude?
Newly diagnosed hypertension is associated with significantly prolonged VEP P100 latency, indicating early subclinical disturbances in the visual pathway prior to symptom onset.
Answers are grounded in this paper and cite their sources.
May indicate early subclinical visual pathway changes in hypertension; hypothesis-generating and should not yet change practice.
Purpose: Blood Pressure (BP) is the pressure of circulating blood against the walls of blood vessels, and high blood pressure or hypertension is the condition in which the blood pressure is too high. Hypertension may affect different body organs. The visual system, mainly the visual pathway, may be affected by hypertension. The aim of the present study is to find out the possible effect of hypertension on the visual pathway using visual evoked potential. Materials and Methods: Twenty-five patients (50 eyes) from 11 male and 14 female patients suffering from hypertension, were selected for the purpose of the present study. The patients were 47-67 years old. The patients had normal Best Corrected Visual Acuity (BCVA). Visual evoked potential (VEP) was tested including Latency (msec) and amplitude (µv) of VEP P100 peak were measured in the patients. The same procedure was done for 25 patients (50 eyes) from a control group with ordinary blood pressure, matched in terms of age, sex and BCVA. The results obtained in the two groups were compared to look for possible differences. Results: There was a statistically significant difference between the case and control groups as far as latency of VEP P100 was concerned (P < 0.001), whereas no statistically significant difference was observed in amplitude between the case and control groups (P = 0.78). Conclusion: Hypertension might affect the visual pathway of patients, which might be observed using VEP.
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Sahbaei et al. (2025) conducted a case-control in Hypertension (n=50). Hypertension vs. Ordinary blood pressure was evaluated on Latency of VEP P100 peak (p=<0.001). Hypertension was associated with a significantly prolonged visual evoked potential P100 latency (106 msec) compared to normotensive controls (99.76 msec, p < 0.001).
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