Effectiveness of 675 nm Laser in Melasma Treatment: 1-Year Follow-Up

Background: Melasma is a cutaneous pigmentary condition, difficult to treat due to its multifactorial chronic nature and high recurrence rates. Objective: To investigate the medium-term and long-term efficacy of the 675 nm laser for the treatment of facial melasma with pigmentary and vascular symptoms. Methods: Eight patients with facial melasma and Fitzpatrick phototypes III to IV were recruited. Three sessions were carried out with a 675-nm laser device. At 5 months and 12 months after the last treatment, the patient’s skin was evaluated from baseline using a five-point Global Aesthetic Improvement Scale (GAIS). Results: The study findings revealed a better overall appearance of the skin condition, in particular GAIS improvements mainly in the visible and pigmented components. Conclusion: The 675-nm laser appears to be effective when treating patients with Fitzpatrick phototypes III to IV for facial melasma, with promising long-term results.