Key result
Major sex-specific differences shape CVD burden and presentation, underscoring the need for female-focused trials.
Why the study?
There are substantial knowledge gaps regarding sex- and gender-specific differences in cardiovascular disease affecting diagnosis, management, and outcomes in women and men.
Supports sex-specific CVD evaluation in practice; leaves open validated strategies for women due to trial underrepresentation.
Accompanying this issue of CMAJ is a special supplement entitled “A comprehensive view of sex-specific issues related to cardiovascular disease” (available online at [www.cmaj.ca/cgi/content/full/176/6/S1][1]).[1][2] The supplement was prepared by myself and other members of the GENESIS (Gender
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Louise Pilote (2007) conducted an editorial in Cardiovascular disease. There are major sex-specific differences in the burden, risk factors, and presentation of cardiovascular disease, highlighting a critical need for large-scale studies adequately representing women.
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