Key result
Incorporating torsion into 3D LV reconstruction reduces viscous energy loss by ~4% in CFD modeling.
Why the study?
The effect of left ventricle torsional motion on LV hemodynamics is not fully understood.
Does incorporating torsion into 3D echocardiography-based reconstruction of the left ventricle alter simulated intraventricular hemodynamics?
Does incorporating torsion into 3D echocardiography-based reconstruction of the left ventricle alter simulated intraventricular hemodynamics?
Absolute Event Rate: 2.879% vs 2.993%
Incorporating torsional motion into 3D echocardiography-based computational fluid dynamics simulations of the left ventricle does not alter overall volumes but significantly impacts local hemodynamics such as wall shear stress and fluid residence time.
Torsion inclusion alters simulated LV hemodynamics in animal models; leaves open translation to clinical 3D echo reconstructions.
In addition to systolic contraction and diastolic relaxation, torsional motion is an essential component of left ventricle (LV) wall motion, but its effect on LV hemodynamics is not fully understood. To this end, the measured rotation of short‐axis sections is incorporated into our 3D reconstruction of LV from 2D echocardiography, which serves as input to the curvilinear immersed boundary framework for LV flow simulations. The geometry is validated against sonomicrometry measurements, whose difference is found to be within the typical myocardium thickness range, and the flow is validated against intracardiac flow velocity measured by Doppler ultrasound. To assess the impact of torsion, two simulations (one including torsion and one without in the reconstruction from the same set of images) are compared. It is found that including torsion in reconstruction for a normal LV does not change the geometry, and consequently the volume and flow rates, due to the circular shape of LV short‐axis sections. However, the time‐averaged wall shear force increases by 12.6% during systole and drops by 4.9% during diastole when torsion is included. Torsion also reduces washout efficiency for this subject, as the volume of fluid with residence time under one cycle is 16.6% lower, while fluid staying 1–2 cycles increases by 3.7%. Viscous frictional energy loss decreases by 3.8% for LV with torsion.
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Sirani et al. (2026) studied Normal left ventricle mechanics (n=1). Incorporation of torsion into 3D left-ventricle reconstruction vs. Reconstruction without torsion was evaluated on Viscous frictional energy loss (e loss) in J/lit. Incorporating torsion into the 3D left-ventricle reconstruction reduced viscous frictional energy loss by 3.8% and decreased washout efficiency, lowering fresh fluid volume by 16.6%.
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