Key result
Treatment with a fixed combination of Losartanum and Amlodipinum significantly decreased systolic and diastolic blood pressure (p=0.000) and reduced pulse-wave velocity from 15.2 to 13.6 m/s (p=0.01).
Why the study?
The safety of calcium channel blockers and angiotensin II receptor blockers during heat waves and their influence on seasonal variability of cardiovascular risk factors in arterial hypertension patients is controversial.
Observational (n=26)
Absolute Event Rate: 13.6% vs 15.2%
p-value: p=0.01
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Смирнова et al. (2017) conducted an observational in arterial hypertension (n=26). Fixed combination of Losartanum and Amlodipinum vs. Baseline was evaluated on Pulse-wave velocity (m/s) (p=0.01). Treatment with a fixed combination of Losartanum and Amlodipinum significantly decreased systolic and diastolic blood pressure (p=0.000) and reduced pulse-wave velocity from 15.2 to 13.6 m/s (p=0.01).
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