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Lung adenocarcinoma presents with trunk patches, splenomegaly, lymphadenopathy, and elevated IgG4 and IL-6 levels.
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This clinical challenge presents a patient with a history of lung adenocarcinoma, violaceous-to-brown cutaneous lesions, splenomegaly, multicentric lymphadenopathy, and elevated ESR, IgG, IgG4, IgA, and IL-6.
A patient with a history of lung adenocarcinoma had violaceous-to-brown cutaneous patches and plaques. Computed tomography showed splenomegaly and multicentric lymphadenopathy, and laboratory testing showed an elevated erythrocyte sedimentation rate and levels of IgG, IgG4, IgA, and interleukin 6. What is the diagnosis and what would you do next?
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Teng et al. (2026) studied this question. A patient with lung adenocarcinoma presented with brown trunk patches, splenomegaly, multicentric lymphadenopathy, and elevated IgG4 and IL-6 levels.
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