Clinical and pathological factors associated with eGFR slope in IgA nephropathy: a single-center retrospective cohort study

=0.130). UACR and T2 estimates remained negative under HC3 inference and after excluding influential observations, although T2 was less stable in some restricted analyses. Baseline albuminuria was the most consistent adverse marker of eGFR slope. T2 lesions were linked to faster decline as well, but this estimate derived from only 16 patients (8.9%) and lost statistical significance when analysis was restricted to ≥5 measurements, making the finding tentative and strictly hypothesis-generating.