Key result
Postoperative gastrointestinal surgery linked to ~44% absolute higher mortality than medical management.
Why the study?
Factors influencing mortality in patients developing gastrointestinal complications after cardiac surgery were not well defined.
Cohort (n=2,054)
No
Absolute Event Rate: 44% vs 0%
p-value: p=<0.01
High mortality after GI complications post-cardiac surgery warrants vigilance in advanced heart failure; leaves open optimal prevention strategies.
This study sought to determine which factors influence the mortality rate in patients developing gastrointestinal complications following cardiac surgery. Between July 1988 and January 1992, 2054 patients underwent cardiac surgical procedures at the Boston University Medical Center Of these. 29 (1.4%) developed postoperative gastrointestinal complications. The overall mortality rate among these patients was 27% (8/29). Those who died following such complications had a higher incidence of New York Heart Association (NYHA) class IV and unstable symptoms (8/8. 100% versus 3/21. 14%; P< 0.0001). and an increased need for preoperative Intra-aortic balloon pump support (4/8. 50%. versus 1/21, 5%; P<0.004). The need for Gastrointestinal surgical intervention increased the mortality rate significantly cmpared with patients managed medically (8/18. 44% versus 0/11. 0%; P<0.01). Patients with ischemic bowel also had a significantly higher mortality (5/5, 100% versus 3/24, 12%: P< 0.001). It is concluded that most patients with gastrointestinal complications following cardiac surgery can be treated, and with acceptable mortality rates. The presence of unstable symptoms preoperative intra-aortic balloon pump support, ischemic bowel and the need for gastrointestinal surgical intervention adversely affect mortality.
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Lazar et al. (1995) conducted a cohort in Gastrointestinal complications following cardiac surgery (n=2,054). Gastrointestinal surgical intervention vs. Medical management was evaluated on Mortality (p=<0.01). Gastrointestinal surgical intervention for postoperative complications was associated with significantly higher mortality compared to medical management (44% vs 0%; P<0.01).
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