Key result
Left lateral pathway location is linked to ~97% ablation success in WPW syndrome.
Why the study?
The relationship between accessory pathway location, electrophysiologic characteristics, and ablation success in WPW syndrome was not well defined.
Observational (n=178)
May guide ablation planning in WPW; leaves open whether location predicts success in prospective cohorts.
BACKGROUND: To investigate the relationship between the location of accessory pathways, electrophysiologic characteristics, and ablation success in Wolfe-Parkinson-White (WPW) syndrome. METHODS: Electrophysiologic study was performed in 178 patients for a pre-excitation syndrome. Accessory pathway location, anterograde or retrograde conduction, ablation success, and recurrence rate were evaluated. RESULTS: Among 178 patients with WPW syndrome, the most frequent location of the accessory pathway was left lateral (39.3%) which had high ablation success rate (97%) and low recurrence rate (1%). A meaningful relationship exists between accessory pathway location and electrophysiologic characteristics. Ablation success rate was 89.7% and was statistically related to accessory pathway location. Recurrent occurred in 2.9% of our patients and was more frequent in right free wall and PJRT. CONCLUSIONS: The location of accessory pathways has a great impact on conductivity, ablation success, and recurrence rate in WPW syndrome.
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Ardakani et al. (2019) conducted an observational in Wolfe-Parkinson-White (WPW) syndrome (n=178). Accessory pathway location was evaluated on Ablation success and recurrence rate. Accessory pathway location significantly impacted ablation success in WPW syndrome, with an overall success rate of 89.7% and a 97% success rate for left lateral pathways.
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