Key result
Treatment of depression immediately after myocardial infarction contraindicates all traditional antidepressants, though alprazolam may offer advantages early in the recovery phase.
Why the study?
Depression is a common problem after myocardial infarction and requires careful diagnosis and treatment consideration due to medical status and medication safety.
Answers are grounded in this paper and cite their sources.
Supports cautious nonpharmacologic management of post-MI depression initially; leaves open contemporary pharmacologic options pending higher-level evidence.
Depression is a common problem after myocardial infarction. Diagnosis is facilitated by use of the criteria for depression in the Diagnostic and Statistical Manual of Mental Disorders and self-rating questionnaires. Treatment may involve both psychological and pharmacologic interventions. The patient's medical status must be carefully assessed before administration of antidepressant medication. All antidepressants are contraindicated immediately after myocardial infarction. When signs and symptoms of depression are exhibited early in the recovery phase, alprazolam (Xanax) may offer advantages over more traditional antidepressants. Further research is necessary to determine the safety of newer antidepressants.
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Kavan et al. (1991) conducted a review in Depression after acute myocardial infarction. Antidepressants and psychological interventions was evaluated. Treatment of depression immediately after myocardial infarction contraindicates all traditional antidepressants, though alprazolam may offer advantages early in the recovery phase.
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