Key result
AcQMap ablation yields ~81% acute procedural success in persistent AF and atypical flutter.
Why the study?
The feasibility, acute and short-term efficacy, and safety of the novel AcQMap High Resolution Imaging and Mapping System for ablation of persistent AF and atypical atrial flutter were not established.
Observational (n=21)
No
AcQMap ablation shows limited durability in persistent AF; leaves open its role pending randomized trials.
INTRODUCTION: The AcQMap High Resolution Imaging and Mapping System was recently introduced. This system provides 3D maps of electrical activation across an ultrasound-acquired atrial surface. METHODS: We evaluated the feasibility and the acute and short-term efficacy and safety of this novel system for ablation of persistent atrial fibrillation (AF) and atypical atrial flutter. RESULTS: A total of 21 consecutive patients (age (mean ± standard deviation) 62 ± 8 years, 23% female) underwent catheter ablation with the use of the AcQMap System. Fourteen patients (67%) were treated for persistent AF and 7 patients (33%) for atypical atrial flutter. Eighteen patients (86%) had undergone at least one prior ablation procedure. Acute success, defined as sinus rhythm without the ability to provoke the clinical arrhythmia, was achieved in 17 patients (81%). At 12 months, 4 patients treated for persistent AF (29%) and 4 patients treated for atypical flutter (57%) remained in sinus rhythm. Complications included hemiparesis, for which intra-arterial thrombolysis was given with subsequent good clinical outcome (n = 1), and complete atrioventricular block, for which a permanent pacemaker was implanted (n = 2). No major complications attributable to the mapping system occurred. CONCLUSION: The AcQMap System is able to provide fast, high-resolution activation maps of persistent AF and atypical atrial flutter. Despite a high acute success rate, the recurrence rate of persistent AF was relatively high. This may be due to the selection of the patients with therapy-resistant arrhythmias and limited experience in the optimal use of this mapping system that is still under development.
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Liebregts et al. (2021) conducted an observational in Persistent atrial fibrillation and atypical atrial flutter (n=21). AcQMap High Resolution Imaging and Mapping System was evaluated on Acute success (defined as sinus rhythm without the ability to provoke the clinical arrhythmia). Ablation using the AcQMap System achieved an 81% acute success rate in persistent atrial fibrillation and atypical atrial flutter, though only 29% of persistent AF patients remained in sinus rhythm at 12 months.
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