Key result
Typical chest pain during AMI linked to ~46% lower reporting odds in recent decades.
Why the study?
The influence of age on delay time, experienced symptoms, and predictors of delay in seeking treatment for acute myocardial infarction was unclear.
Observational (n=23,543)
Yes
Odds Ratio: 0.54 (95% CI 0.48–0.6)
Absolute Event Rate: 80% vs 83.5%
p-value: p=< 0.001
Clinicians should heighten suspicion for atypical AMI presentations; this observational trend leaves open its drivers and clinical impact.
A secondary analysis was conducted from data gathered from 239 patients with acute myocardial infarction presenting to the emergency departments of three hospitals to explore the influence of age on delay time, experienced symptoms, and factors predicting a delay of >1 hour. During hospitalization, a structured interview about the patients' experience before hospital admission was completed and their medical records were reviewed. The median delay before seeking treatment was not significantly different between older (2.5 hours) and younger patients (2.1 hours). Older patients were significantly less likely to report classic pain in the center of the chest and other associated symptoms such as sweating and nausea; they also used fewer words to describe their discomfort compared with younger patients. Independent predictors of longer delay were: contacted physician, lacked similarity between experienced and expected symptoms, did not use 911 (older adults), lived alone, and contacted physician (younger adults). Primary care providers need to be aware that elderly persons are more likely to have mild or ambiguous acute myocardial infarction symptoms and education is needed for elderly persons regarding not only acute myocardial infarction symptoms but also rapid, action-centered decisions to attribute symptoms to heart problems and initiate ambulance use.
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Hwang et al. (2006) conducted an observational in Acute Myocardial Infarction (n=23,543). Time period of AMI occurrence (2006-2019) vs. 1985-1995 (reference period) was evaluated on Reporting of typical chest pain (OR 0.54, 95% CI 0.48-0.60, p=< 0.001). Between 1985 and 2019, the odds of patients reporting typical chest pain during an acute myocardial infarction significantly decreased (OR 0.54) compared to the 1985-1995 reference period.
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