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It has been shown (Conway & Hingerty, 1948) that sodium ions which had entered muscle extensively in rats on a potassium-free diet were actively extruded on changing the animals to a potassium- rich diet.The mean half period of extrusion, even with the plasma potassium above the normal level within 24 hr.after the change, was about 3 days.Very recently, Desmedt (1953) has described a more rapid net excretion of sodium ions from the isolated frog sartorius in which sodium ions had entered extensively after immersion in a potassium-free Ringer solution in the manner described by Steinbach (1951).To demonstrate the excretion, companion muscles which were similarly treated
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Conway et al. (1954) studied this question.
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