Key result
PARV4 DNA shows distinct tropism, persisting in ~49% of myocardial and liver tissue samples.
Why the study?
PARV4 prevalence in human tissues and its ability to persist compared to parvovirus B19 have not been clearly established.
Observational (n=136)
No immediate change to clinical practice; leaves open PARV4's role in chronic cardiac or hepatic disease.
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Corcioli et al. (2010) conducted an observational in Without suspected acute viral infection (n=136). PARV4 infection vs. Parvovirus B19 (B19V) infection was evaluated on Detection frequency of viral DNA in various tissues. PARV4 DNA was frequently detected in the myocardium (49%) and liver (41%) of adults without acute viral infection, suggesting a particular tropism for these tissues compared to other organs.
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