Key result
Review outlines cardiovascular effects, drug interactions, and clinical use of newer antidepressants in cardiovascular disease.
Why the study?
The cardiovascular effects of commonly used novel antidepressants and their interactions with cardiovascular medications require comprehensive review.
Review of novel antidepressant CV effects to 2001; leaves open relevance of newer agents and interactions in current cardiac practice.
This paper reviews the current knowledge of cardiovascular effects of the most commonly used novel antidepressants and their possible interactions with cardiovascular medications. The literature was reviewed through Medline 1980-2001. Materials were located by using terms such as SSRIs, individual names of novel antidepressants matched with terms like cardiovascular effects, cardiovascular diseases, cardiovascular risk factors, etc. Drug compendiums from 1998-2001 and some psychopharmacology texts were also used. The article focuses on the cardiovascular effects of the newer antidepressants, their use in patients with cardiovascular disease, and interactions with various commonly used cardiovascular drugs.
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Khawaja et al. (2003) conducted a review in Cardiovascular disease. Selective Serotonin Reuptake Inhibitors and Other Novel Antidepressants was evaluated. This review summarizes the cardiovascular effects of newer antidepressants, their use in patients with cardiovascular disease, and interactions with commonly used cardiovascular drugs.
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