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March 1, 1991Journal of Vacuum Science & Technology B Microelectronics and Nanometer Structures Processing Measurement and Phenomena

A technique for stable adhesion of DNA to a modified graphite surface for imaging by scanning tunneling microscopy

Yuri L. Lyubchenko Stuart Lindsay James DeRose Thomas Thundat

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Abstract

A procedure has been developed in which mercurated DNA is covalently bonded to a modified graphite surface. This technique allows for stable adhesion of the DNA which enables one to image it with the scanning tunneling microscope. The method is outlined in this paper and images are presented of a partially modified graphite surface and one completely modified with DNA attached. The DNA images demonstrate B-helix periodicity.

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Lyubchenko et al. (1991) studied this question.

synapsesocial.com/papers/6acc61e04ba5e6b62b803330 https://doi.org/10.1116/1.585223

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