Reflector‐Free, Highly Confined Love‐Like SAWs Enabled by a Phononic Metasurface for Real‐Time Monitoring of Cell Dynamics

Surface acoustic wave (SAW) devices are widely used in sensing and biosensing but generally suffer from strong attenuation in liquid environments. Conventional approaches rely on reflectors to reduce these losses, yet these components remain difficult to optimize: limited device miniaturization and increased fabrication complexity. Here, we introduce an innovative design strategy that integrates a phononic metasurface with tailored electromechanical properties of the substrate to generate a type of shear‐horizontal (SH) surface resonance modes that exhibit strong lateral confinement and extremely low radiation into both the substrate bulk and the free surface, eliminating the need for reflectors. This approach enables highly tailorable surface acoustic resonances with distinctive enhanced dynamic strain‐energy confinement leading to significantly high‐quality factors, particularly in water‐loaded conditions. We show the fabrication and experimental validation of the proposed phononic metasurface‐based SAW resonator and showcase its biosensing capabilities through real‐time monitoring of cellular death.