Key result
Radical surgical resection utilizing liver transplantation techniques successfully treated an extensive late-relapsed germ cell tumour caval thrombus, with the patient disease-free at two years.
Why the study?
Up to 3.2% of patients with testicular germ cell tumours experience late relapse, and aggressive surgical resection offers the greatest chance of cure in this group.
Case Report (n=1)
No
Techniques derived from liver transplantation can enable successful, complete resection of complex and extensive caval and hepatic vein tumour thrombi in patients with late-relapsing germ cell tumours.
May expand resectability for complex caval thrombi in late-relapsed germ cell tumors; leaves open need for validation beyond single cases.
Up to 3.2% of patients with testicular germ cell tumours represent with late-relapsing disease. Aggressive surgical resection confers the greatest chance of cure in this patient group. We present the case of a late and extensively relapsed nonseminomatous germ cell tumour with thrombus present along the entire length of the inferior vena cava, as well as in the right hepatic vein. Techniques practised in liver transplantation were used to achieve complete resection of the tumour thrombus. This case illustrates the enhanced potential for tumour resection through a fusion of principles derived from surgical oncology and liver transplantation.
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Leidhin et al. (2014) conducted a case report in Late-relapsed nonseminomatous germ cell tumour with extensive caval and hepatic vein tumour thrombus (n=1). Radical surgical resection (hepatectomy, cavotomy, and thrombectomy) was evaluated on Surgical success and disease-free survival. Radical surgical resection utilizing liver transplantation techniques successfully treated an extensive late-relapsed germ cell tumour caval thrombus, with the patient disease-free at two years.
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