Key result
Aortic and caval reconstruction yields 30-month disease-free survival with patent grafts in metastatic germ cell tumor.
Case Report (n=1)
No
Prosthetic aortic and IVC reconstruction appears feasible after chemotherapy in metastatic germ cell tumors; this single case leaves open durability and broader applicability.
A 49-year-old man who had a huge testicular tumor with retroperitoneal lymph node metastasis and bilateral multiple pulmonary metastases was referred to our hospital. Firstly orchiectomy was done obtaining the pathological diagnosis of mixed type germ cell tumor. After cisplatin-based chemotherapy, he underwent resection of the retroperitoneal lymph node involving the abdominal aorta and the inferior vena cava. Both great vessels were resected with the tumor and reconstructed with prosthetic grafts. Two months after the laparotomy, 12 metastatic nodules in the left lung were resected. Seven months later, he furthermore underwent resection of 4 metastatic nodules in the right lung. Microscopically, all resected metastatic tumors were diagnosed to be mature teratoma without viable malignant cells. The patient remains well 30 months after the first operation. Follow-up CT scan demonstrates patency of aortic and vena caval bypass grafts without local recurrence or distant metastasis.
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Hara et al. (2005) conducted a case report in Metastatic germ cell tumor (n=1). Aortic and vena caval reconstruction with retroperitoneal lymph node dissection and pulmonary metastasectomy was evaluated on Clinical outcome and graft patency. Aortic and vena caval reconstruction with retroperitoneal lymph node dissection achieved 30-month disease-free survival with patent bypass grafts in a patient with metastatic germ cell tumor.
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