Key result
Creating a durable bioprosthetic valve requires well-designed in vitro hydrodynamic studies, in vivo preclinical animal studies, and high-quality first-in-human clinical studies.
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The use of bioprosthetic valves for aortic and mitral valve replacement is becoming increasingly popular.1,2 Given the projected dramatic increase in the elderly population in the near future, there is an increasing need for durable bioprosthetic valves. The ideal bioprosthetic valve should have excellent hemodynamic performance, a minimal risk of structural valve deterioration, excellent functional outcomes, and low valve-related morbidity and mortality. Creating such a valve requires well-designed in vitro hydrodynamic performance studies, in vivo preclinical animal studies, and high-quality first-in-human clinical studies.
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Ko Bando (2020) conducted an editorial in Aortic and mitral valve disease. Bioprosthetic valves was evaluated. Creating a durable bioprosthetic valve requires well-designed in vitro hydrodynamic studies, in vivo preclinical animal studies, and high-quality first-in-human clinical studies.
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