Key result
Beta-blocker therapy is linked to lower MRI-specific anxiety during CMR.
Why the study?
Patient distress during cardiac magnetic resonance imaging may affect breath-hold performance and image quality, with unclear influence of MRI experience, sex, or beta-blocker therapy.
Does beta-blocker therapy reduce anxiety and improve image quality in patients undergoing early post-infarction CMR?
Observational (n=53)
Does beta-blocker therapy reduce anxiety and improve image quality in patients undergoing early post-infarction CMR?
p-value: p=0.01
Patients not receiving beta-blockers experience higher MRI-specific anxiety during post-infarction CMR and may require enhanced procedural reassurance and preparation.
Beta-blocker therapy was associated with lower MRI-specific anxiety; supports targeted preparation for non-users but leaves effects on breath-hold and image quality open.
INTRODUCTION: Cardiac magnetic resonance (CMR) is performed in a confined scanner environment and requires patient cooperation during repeated breath-holds, factors that may contribute to distress. This mixed-methods study examined how patient experiences, emotional states, and perceived distress influence breath-hold performance and image quality during CMR, and whether these relationships differ by previous magnetic resonance imaging (MRI) experience, sex or beta-blocker therapy. METHODS: Fifty-three patients undergoing early post-infarction CMR were included. State anxiety was assessed before and after CMR, and MRI-specific anxiety post-scan. Breath-hold effort, duration and heart rate were recorded across predefined sequences. Image quality was rated using a predefined scale. Sixteen semi-structured interviews were analysed using reflexive thematic analysis. RESULTS: State anxiety decreased modestly after CMR (p = 0.01), with no differences related to previous MRI experience or beta-blocker therapy. MRI-specific anxiety was significantly higher among patients not receiving beta-blocker therapy, consistent with qualitative reports of bodily stress and claustrophobic sensations. Patients receiving beta-blockers described calmer emotional states. Perceived breath-hold effort was light to moderate and comparable across subgroups. Overall image quality was high, with respiratory ghosting in Grid-tagging short axis (SAX) and blurring and mis-triggering in Cine and late gadolinium enhancement SAX sequences. CONCLUSION: Beta-blocker therapy was associated with lower MRI-specific anxiety but not general state anxiety, suggesting modulation of scanner-related physiological arousal. Procedural and emotional factors shaped cooperation during CMR. IMPLICATIONS FOR PRACTICE: Patients not receiving beta-blockers may benefit from enhanced preparatory information and reassurance. Clear communication, breath-hold guidance and protocol flexibility may support comfort, cooperation and diagnostic image quality.
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Wahlström et al. (2026) conducted an observational in Early post-infarction (n=53). Beta-blocker therapy vs. No beta-blocker therapy was evaluated on State anxiety and MRI-specific anxiety (p=0.01). Beta-blocker therapy was associated with lower MRI-specific anxiety during CMR, while overall state anxiety decreased modestly post-scan across all patients (p=0.01).
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