Key result
Baseline SF-12 physical score matches handgrip strength for predicting reduced 3-month functional exercise capacity.
Why the study?
The comparative performance of patient-reported physical health and muscle strength for identifying reduced functional exercise capacity in older adults with ischaemic heart disease remains unclear.
Do baseline SF-12 PCS and handgrip strength reliably identify reduced functional exercise capacity at 3 months in older adults with ischaemic heart disease?
Observational (n=350)
Do baseline SF-12 PCS and handgrip strength reliably identify reduced functional exercise capacity at 3 months in older adults with ischaemic heart disease?
Odds Ratio: 0.776 (95% CI 0.657–0.916)
Brief assessments using SF-12 PCS or handgrip strength provide comparable and adequate discrimination to identify reduced functional exercise capacity, offering a feasible alternative when 6-minute walk tests cannot be immediately performed.
SF-12 PCS or handgrip strength may identify reduced exercise capacity post-IHD; hypothesis-generating and requires prospective validation before practice change.
Background Brief assessments may help identify reduced functional exercise capacity when walking tests are not immediately feasible. However, the comparative performance of patient-reported physical health and muscle strength remains unclear. This study compared baseline 12-Item Short Form Health Survey Physical Component Summary (SF-12 PCS), handgrip strength (HGS), and their combination for identifying reduced functional exercise capacity at 3 months in older adults with ischaemic heart disease.Methods This secondary analysis included participants with complete baseline SF-12 PCS, HGS, sex, and 3-month six-minute walk distance (6MWD) data. Reduced functional exercise capacity was defined as 6MWD <350 m. Discrimination was assessed using sex-adjusted logistic regression models and receiver operating characteristic analysis. Exploratory cut-offs were determined using the Youden index.Results Among 350 participants, 57 (16.3%) had reduced functional exercise capacity. SF-12 PCS and HGS showed comparable discrimination (AUC 0.739 and 0.743, respectively), while the combined model yielded the highest AUC (0.777; 95% CI 0.715–0.839), with no significant pairwise differences. Exploratory cut-offs were ≤40.25 points for SF-12 PCS and ≤35.38 kg for men and ≤18.14 kg for women for HGS. In the comorbidity-adjusted model, higher SF-12 PCS (OR 0.776, 95% CI 0.657–0.916) and HGS (OR 0.736, 95% CI 0.605–0.897) were associated with lower odds of reduced functional exercise capacity.Conclusions SF-12 PCS and HGS showed comparable discrimination, with no significant incremental benefit from their combination. These brief assessments may support initial physiotherapy evaluation when the six-minute walk test is not immediately feasible but should complement direct assessment. The exploratory cut-offs require external validation.
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Aueyingsak et al. (2026) conducted an observational in ischaemic heart disease (n=350). SF-12 Physical Component Summary (PCS) and Handgrip Strength (HGS) was evaluated on Reduced functional exercise capacity (6MWD <350 m) at 3 months (OR 0.776, 95% CI 0.657-0.916). Baseline SF-12 physical component summary and handgrip strength showed comparable discrimination for identifying reduced functional exercise capacity at 3 months (AUC 0.739 and 0.743, respectively).
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