Key result
Surgical resection of rare tricuspid valve leiomyosarcoma metastasis restores cardiac function.
Why the study?
Uterine leiomyosarcoma is a rare malignancy with poor prognosis that can metastasize to distant organs including the heart, but cardiac valve metastasis is rarely reported and may cause severe complications.
Case Report (n=1)
Resection may stabilize rare tricuspid metastases from uterine leiomyosarcoma; single case leaves open generalizability and need for prospective data.
Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs. It presents with symptoms of abdominal distension, vaginal bleeding and may pass unnoticed until an advanced stage in patients with leiomyomas. Surgery is a viable option in patients with disease limited to the uterus, but metastasis to the heart may require surgery to prevent acute and catastrophic complications. The case described here involves metastasis to the tricuspid valve, which caused severe tricuspid regurgitation in the setting of acute pulmonary embolism. Surgical resection restored cardiac function and stabilized the patient. This case illustrates a rare site of metastasis of leiomyosarcoma which required immediate intervention and resulted in a favorable outcome.
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Marak et al. (2013) conducted a case report in Uterine Leiomyosarcoma with metastasis to the tricuspid valve (n=1). Surgical resection was evaluated. Surgical resection of a rare uterine leiomyosarcoma metastasis to the tricuspid valve restored cardiac function and stabilized the patient following presentation with severe tricuspid regurgitation.
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