Key result
Sequential radiotherapy and chemotherapy provide symptom relief in rare interventricular septum leiomyosarcoma metastasis.
Why the study?
Metastases of uterine leiomyosarcoma to the heart are extremely rare with limited published case reports.
Case Report (n=1)
May support palliative RT plus chemotherapy for symptom relief in rare cardiac metastases; hypothesis-generating and should not change practice.
Uterine leiomyosarcoma is an uncommon and aggressive gynecologic malignancy with an overall poor prognosis. Lungs, bones and brain are common sites of metastases of uterine leiomyosarcoma. Metastases of uterine leiomyosarcoma to the heart are extremely rare, and only a few case reports have been published so far. Herein we present the case of 57 years old female, who had undergone total abdominal hysterectomy with salpingo-oophorectomy 10 years back for uterine leiomyosarcoma, she presented with dyspnea, dizziness, fever, and tachycardia, subsequently was found to have interventricular septum cardiac as well extensive system metastasis and recurrent pelvic mass. Patient's symptoms responded to palliative radiotherapy followed by chemotherapy.
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Tunio et al. (2014) conducted a case report in Uterine leiomyosarcoma metastasizing to the heart (n=1). Palliative radiotherapy followed by chemotherapy was evaluated on Symptom response. Palliative radiotherapy followed by chemotherapy improved symptoms in a 57-year-old woman with an extremely rare presentation of uterine leiomyosarcoma metastasizing to the interventricular septum.
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