Key result
Higher TyG-ABSI linked to ~4-fold higher CVD risk, outperforming standard adiposity indices.
Why the study?
The predictive value of combining the triglyceride-glucose (TyG) index with novel body shape indices for cardiovascular disease risk remains unclear.
Does combining the TyG index with novel body shape indices improve the prediction of cardiovascular disease in adults?
Cross-Sectional (n=19,822)
Yes
Does combining the TyG index with novel body shape indices improve the prediction of cardiovascular disease in adults?
Odds Ratio: 3.95 (95% CI 1.99–7.85)
p-value: p=<0.05
Combining the TyG index with body-shape indices, particularly TyG-ABSI, improves cardiovascular disease risk prediction and may serve as a cost-effective tool for early risk assessment.
TyG-ABSI may enhance CVD risk prediction; hypothesis-generating and should not yet change practice.
No takes yet. Share an insight, caveat, or question.
Zheng et al. (2026) conducted a cross-sectional in Cardiovascular disease (n=19,822). TyG index combined with body shape indices (e.g., TyG-ABSI, TyG-BRI) was evaluated on Cardiovascular disease (CVD) by self-reported physician diagnosis (OR 3.95, 95% CI 1.99-7.85, p=<0.05). The TyG-ABSI index was strongly associated with higher cardiovascular disease risk (OR 3.95; 95% CI 1.99-7.85), outperforming the TyG index and other body shape indices in discriminative power.
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