Key result
Unstable blood pressure linked to ~7.8-fold higher odds of cardiogenic shock in post-MI patients.
Why the study?
The nursing diagnosis Risk for shock in patients with AMI admitted to ICU required clinical validation to identify accurate predictive indicators for cardiogenic shock.
What are the independent clinical indicators that accurately predict the development of cardiogenic shock in adult patients with AMI admitted to the ICU?
Case-Control (n=116)
No
What are the independent clinical indicators that accurately predict the development of cardiogenic shock in adult patients with AMI admitted to the ICU?
Odds Ratio: 7.8 (95% CI 3.1–19.6)
p-value: p=<0.001
Four clinical indicators—unstable blood pressure, hypoxia, hypoxemia, and inadequate fluid volume—are strong independent predictors that can help critical care nurses anticipate cardiogenic shock in AMI patients.
Unstable BP, hypoxia, hypoxemia, and fluid deficit may aid early cardiogenic shock anticipation in AMI ICU patients; supports 'Risk for shock' validation but leaves open prospective confirmation.
Objective To clinically validate the nursing diagnosis “Risk for shock” in patients with acute myocardial infarction (AMI) admitted to an Intensive Care Unit (ICU). Method A retrospective case-control study conducted at a high-complexity university hospital in Brazil. The sample consisted of 116 medical records of adult patients with AMI, equally distributed between the case group (with cardiogenic shock; n = 58) and the control group (without cardiogenic shock; n = 58). Diagnostic accuracy measures (sensitivity, specificity, predictive values, and likelihood ratios) were calculated, and multivariate binary logistic regression using the Stepwise Forward method was applied to identify independent predictors and control for confounders. Results In the accuracy analysis, the indicator “Unstable blood pressure” showed the best clinical balance, with a sensitivity of 85.0% (95% CI: 76.2–93.8) and a specificity of 83.6% (95% CI: 74.4–92.8). “Hyperthermia” and “Inadequate fluid volume” showed the highest individual specificities (90.1% and 80.3%, respectively). After adjusting the logistic regression model (Nagelkerke R 2 = 0.614; Hosmer-Lemeshow p = 0.782), only four factors remained significant as independent predictors of the outcome: unstable blood pressure (aOR = 7.80; 95% CI: 3.10–19.60; p < 0.001), hypoxia (aOR = 3.70; 95% CI: 1.50–9.20; p = 0.006), hypoxemia (aOR = 2.90; 95% CI: 1.40–6.10; p = 0.004), and inadequate fluid volume (aOR = 2.10; 95% CI: 1.00–4.50; p = 0.048). Thermal and hemorrhagic indicators lost significance after adjustment. Conclusion The study clinically validated the diagnosis and confirmed a robust predictive model composed of four indicators. Prioritizing the monitoring of these risk factors enables critical care nurses to anticipate hemodynamic collapse, support targeted care protocols, and optimize multiprofessional decision-making at the bedside.
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Dantas et al. (2026) conducted a case-control in Acute myocardial infarction (AMI) (n=116). Unstable blood pressure vs. Without unstable blood pressure was evaluated on Cardiogenic shock (aOR 7.80, 95% CI 3.10-19.60, p=<0.001). Unstable blood pressure was the strongest independent predictor of cardiogenic shock in ICU patients with acute myocardial infarction (aOR 7.80; 95% CI 3.10-19.60; p<0.001).
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