Squamous Cell Carcinoma of the Seminal Vesicle from Zinner Syndrome: A Case Report and Review of Literature

Until now, fewer than 60 cases of tumors originating from the seminal vesicle have been reported. Most of them were adenocarcinoma, cystadenoma, and benign mesenchymal tumor [1]. Among them, only three cases in the English literature have been reported as squamous cell carcinoma [2-4]. Although all three cases had a prolonged history of stone formation or chronic inflammation, none of them were associated with congenital malformation of the urogenital system such as Zinner syndrome. Zinner syndrome is a rare Mullerian duct abnormality consisting of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. Herein, we report a 41-year-old male with Zinner syndrome, who developed a poorly differentiated squamous cell carcinoma of the seminal vesicle as a result of prolonged inflammation.