Key result
Multimodal imaging and anti-inflammatory therapy or pericardiectomy guide diagnosis and management in constrictive pericarditis.
Why the study?
Constrictive pericarditis is a diagnostic challenge due to overlapping clinical features with other conditions and requires synthesis of evolving diagnostic and management strategies.
A multimodality imaging approach is essential for diagnosing constrictive pericarditis and identifying early inflammatory phases where anti-inflammatory therapy may prevent the need for surgical pericardiectomy.
Supports multimodal imaging and selective therapy in constrictive pericarditis; leaves open optimal surgical timing pending prospective data.
Constrictive pericarditis (CP) is an uncommon but potentially curable cause of heart failure with preserved ejection fraction, in which a fibrotic, inelastic, and often calcified pericardium restricts diastolic filling of the ventricles. The disease remains a diagnostic challenge because its clinical picture overlaps with restrictive cardiomyopathy, severe tricuspid regurgitation, and non-cardiac causes of systemic venous congestion. This review synthesizes the contemporary medical literature on CP, covering its epidemiology and evolving etiologic spectrum, the two cardinal pathophysiologic mechanisms (dissociation of intrathoracic and intracardiac pressures and exaggerated ventricular interdependence), the validated echocardiographic diagnostic criteria, the complementary roles of cardiac magnetic resonance imaging, cardiac computed tomography, and invasive hemodynamics, and current management strategies. Particular emphasis is placed on the identification of transient (inflammatory) constriction, which may resolve with anti-inflammatory therapy, and on the outcomes and risk stratification of radical pericardiectomy, the definitive treatment for chronic disease.
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Farmesk Ibrahim Ridha (2026) conducted a review in Constrictive pericarditis. Constrictive pericarditis requires multimodal imaging for diagnosis, differentiation from restrictive cardiomyopathy, and is managed with anti-inflammatory therapy or radical pericardiectomy.
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